Aron H Lichtman Selected Research

Catalepsy

1/2020	In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects.
12/2015	A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects.
8/2015	Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice.
5/2015	Selective monoacylglycerol lipase inhibitors: antinociceptive versus cannabimimetic effects in mice.
12/2012	Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice.
11/2012	Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in mouse blood and tissue after inhalation exposure to 'buzz' smoke by HPLC/MS/MS.
11/2010	Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol.
7/2010	FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration.
12/2009	Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.
8/2009	Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol.

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Aron H Lichtman Research Topics

Disease

32	Pain (Aches) 01/2022 - 12/2002
20	Neuralgia (Stump Neuralgia) 01/2020 - 10/2004
19	Hyperalgesia 12/2019 - 06/2004
14	Hypothermia 01/2020 - 07/2002
13	Catalepsy 01/2020 - 08/2002
12	Neoplasms (Cancer) 11/2021 - 09/2007
7	Edema (Dropsy) 03/2013 - 06/2004
6	Neurocognitive Disorders (Clerambault Syndrome) 01/2022 - 01/2016
6	Nausea 11/2021 - 01/2012
5	Opioid-Related Disorders (Opiate Addiction) 01/2022 - 11/2002
5	Neuroinflammatory Diseases 12/2021 - 11/2011
5	Peripheral Nervous System Diseases (PNS Diseases) 11/2021 - 11/2016
5	Inflammation (Inflammations) 01/2021 - 07/2004
5	Tobacco Use Disorder (Nicotine Dependence) 10/2020 - 01/2017
4	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2022 - 01/2011
4	Diarrhea 01/2022 - 10/2011
4	Hypersensitivity (Allergy) 01/2021 - 12/2010
3	Weight Loss (Weight Reduction) 01/2022 - 05/2005
3	Vomiting 11/2021 - 01/2012
3	Body Weight (Weight, Body) 02/2020 - 05/2005
3	Chronic Pain 01/2018 - 12/2010
3	Memory Disorders (Memory Loss) 07/2014 - 01/2007
3	Substance-Related Disorders (Drug Abuse) 12/2009 - 11/2002
2	Reperfusion Injury 10/2022 - 04/2012
2	Wounds and Injuries (Trauma) 10/2022 - 01/2017
2	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2021 - 01/2017
2	Anhedonia 09/2020 - 01/2017
2	Multiple Sclerosis 01/2018 - 07/2014
2	Ovarian Neoplasms (Ovarian Cancer) 01/2018 - 01/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 01/2018
2	Cancer Pain 01/2018 - 08/2017
2	Seizures (Absence Seizure) 01/2017 - 05/2003
2	Chronic Disease (Chronic Diseases) 01/2017 - 01/2016
2	Central Nervous System Diseases (CNS Diseases) 01/2017 - 01/2016
2	Pruritus (Itching) 04/2016 - 04/2009
2	Cognitive Dysfunction 01/2016 - 08/2011
2	Hemorrhage 06/2013 - 09/2011
2	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2011 - 08/2007
2	Tremor (Tremors) 10/2011 - 09/2006
2	Visceral Pain 11/2009 - 04/2009

Drug/Important Bio-Agent (IBA)

31	CannabinoidsIBA 10/2022 - 08/2002
23	EnzymesIBA 10/2022 - 12/2002
23	EndocannabinoidsIBA 01/2022 - 12/2002
20	Dronabinol (THC)FDA LinkGeneric 11/2021 - 08/2002
16	anandamide (arachidonylethanolamide)IBA 10/2022 - 12/2002
15	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 10/2022 - 06/2004
14	Cannabinoid Receptors (Cannabinoid Receptor)IBA 10/2022 - 06/2004
12	Pharmaceutical PreparationsIBA 01/2020 - 12/2002
11	Monoacylglycerol LipasesIBA 01/2021 - 12/2010
10	Opioid Analgesics (Opioids)IBA 01/2022 - 11/2002
8	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2022 - 11/2002
8	AmidesIBA 01/2021 - 12/2002
7	Morphine (MS Contin)FDA LinkGeneric 01/2021 - 10/2011
7	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 12/2002
7	JZL 184IBA 01/2018 - 09/2011
7	CarrageenanIBA 01/2017 - 06/2004
6	LipidsIBA 12/2021 - 12/2002
6	RimonabantIBA 10/2011 - 07/2002
5	Naloxone (Narcan)FDA LinkGeneric 01/2022 - 10/2011
5	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 11/2016
5	Nicotine FDA Link 10/2020 - 01/2013
5	Formaldehyde (Formol)FDA Link 01/2020 - 06/2004
5	Analgesics (Analgesic Drugs)IBA 06/2018 - 09/2011
5	Cannabinoid Receptor AgonistsIBA 06/2018 - 07/2010
4	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 12/2021 - 03/2016
4	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2018 - 02/2013
4	MJN110IBA 01/2018 - 02/2015
4	PF 3845IBA 08/2015 - 04/2012
4	cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester (URB597)IBA 04/2014 - 05/2007
3	N-oleoylglycineIBA 01/2021 - 01/2020
3	Trans-Activators (Trans-Acting Factor)IBA 01/2021 - 01/2017
3	LigandsIBA 11/2020 - 04/2012
3	3- (2- hydroxy- 4- (1,1- dimethylheptyl)phenyl)- 4- (3- hydroxypropyl)cyclohexanolIBA 01/2020 - 02/2011
3	Gabapentin (Neurontin)FDA LinkGeneric 06/2018 - 12/2010
3	LipopolysaccharidesIBA 12/2017 - 07/2010
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 09/2014 - 04/2009
3	Diclofenac (SR 38)FDA LinkGeneric 09/2014 - 01/2008
3	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2014 - 01/2008
2	Urea (Carbamide)FDA LinkGeneric 10/2022 - 01/2018
2	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 12/2021 - 12/2017
2	nabilone (Cesamet)FDA Link 11/2021 - 01/2014
2	Viral ProteinsIBA 01/2021 - 03/2013
2	Opiate AlkaloidsIBA 11/2020 - 04/2016
2	CytokinesIBA 11/2020 - 09/2011
2	Lithium ChlorideIBA 02/2020 - 03/2016
2	Sucrose (Saccharose)IBA 01/2020 - 01/2017
2	CannabidiolIBA 01/2018 - 08/2017
2	Fingolimod Hydrochloride (FTY720)FDA Link 01/2018 - 07/2014
2	nabiximols (Sativex)IBA 01/2018 - 08/2017
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2017 - 01/2017
2	HydrolasesIBA 01/2017 - 11/2004
2	piperidineIBA 08/2015 - 05/2015
2	AcidsIBA 04/2014 - 07/2010
2	SmokeIBA 12/2012 - 01/2011
2	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 10/2011 - 12/2010
2	(3R)- ((2,3- dihydro- 5- methyl- 3- ((4- morpholinyl)methyl)pyrrolo- (1,2,3- de)- 1,4- benzoxazin- 6- yl)(1- naphthalenyl))methanone (WIN 55,212)IBA 07/2010 - 02/2008
2	Ethanolamine (Colamine)IBA 01/2008 - 06/2004

Therapy/Procedure

8	Analgesia 01/2018 - 11/2004
7	Drug Therapy (Chemotherapy) 11/2021 - 11/2016
7	Therapeutics 12/2019 - 01/2014